Shozo Yamada Selected Research

Pituitary Neoplasms (Pituitary Adenoma)

4/2022	Efficacy of temozolomide combined with capecitabine (CAPTEM) on refractory prolactinomas as assessed using an ex vivo 3D spheroid assay.
1/2022	Temozolomide and Capecitabine Treatment for an Aggressive Somatotroph Pituitary Tumor: A Case Report and Literature Review.
8/2021	GH-induced LH hyporesponsiveness as a potential mechanism for hypogonadism in male patients with acromegaly.
6/2021	Tumor Shrinkage by Metyrapone in Cushing Disease Exhibiting Glucocorticoid-Induced Positive Feedback.
1/2021	Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease.
4/2020	MSH6/2 and PD-L1 Expressions Are Associated with Tumor Growth and Invasiveness in Silent Pituitary Adenoma Subtypes.
2/2020	Follicle-stimulating Hormone-secreting Pituitary Adenoma Accompanied by Painful Thyroiditis.
8/2019	Successful reduction of ACTH secretion in a case of intractable Cushing's disease with pituitary Crooke's cell adenoma by combined modality therapy including temozolomide.
3/2019	Outcomes of three-Tesla magnetic resonance imaging for the identification of pituitary adenoma in patients with Cushing's disease.
8/2018	Postoperative growth hormone dynamics in clinically nonfunctioning pituitary adenoma.

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Shozo Yamada Research Topics

Disease

56	Pituitary Neoplasms (Pituitary Adenoma) 04/2022 - 01/2002
54	Neoplasms (Cancer) 06/2022 - 01/2002
44	Adenoma (Adenomas) 03/2022 - 01/2002
19	Pituitary ACTH Hypersecretion 06/2022 - 01/2002
17	Acromegaly 01/2022 - 08/2003
15	ACTH-Secreting Pituitary Adenoma 03/2022 - 01/2005
8	Prolactinoma (Prolactinomas) 04/2022 - 12/2002
7	Growth Hormone-Secreting Pituitary Adenoma 05/2016 - 04/2003
4	Insulin Resistance 11/2017 - 10/2008
3	Carcinogenesis 09/2017 - 01/2002
3	Cushing Syndrome 09/2017 - 12/2006
3	Diabetes Mellitus 07/2013 - 12/2006
2	Autoimmune Hypophysitis 01/2022 - 02/2018
2	Hemorrhage 01/2017 - 01/2004
2	Hyperthyroidism 01/2015 - 01/2009
2	Neoplasm Metastasis (Metastasis) 08/2013 - 12/2002
1	Germinoma 01/2022
1	Sarcoidosis (Schaumann Disease) 01/2022
1	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 01/2022
1	Hypopituitarism (Sheehan's Syndrome) 08/2021
1	Hyperprolactinemia 08/2021
1	False Aneurysm (Pseudoaneurysm) 01/2021
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 07/2020
1	Teratoma (Teratoid Tumor) 07/2020
1	Ovarian Cysts (Ovarian Cyst) 02/2020
1	Thyroiditis 02/2020
1	Thyrotoxicosis 02/2020
1	Neck Pain (Cervicalgia) 02/2020

Drug/Important Bio-Agent (IBA)

29	Adrenocorticotropic Hormone (ACTH)FDA Link 06/2022 - 01/2002
25	Growth Hormone (Somatotropin)IBA 01/2022 - 01/2002
13	Hormones (Hormone)IBA 01/2021 - 01/2003
12	Messenger RNA (mRNA)IBA 12/2015 - 08/2003
11	ProlactinIBA 03/2013 - 01/2003
10	Insulin-Like Growth Factor I (IGF-1)IBA 01/2022 - 10/2008
8	Transcription Factors (Transcription Factor)IBA 04/2020 - 01/2002
7	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2022 - 01/2002
7	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2022 - 06/2007
7	Glucose (Dextrose)FDA LinkGeneric 11/2016 - 12/2008
6	Temozolomide (Temodar)FDA LinkGeneric 04/2022 - 10/2009
6	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2021 - 12/2007
6	Proteins (Proteins, Gene)FDA Link 07/2018 - 01/2002
6	DNA (Deoxyribonucleic Acid)IBA 07/2018 - 04/2003
6	Octreotide (Sandostatin)FDA LinkGeneric 01/2015 - 06/2007
6	Cadherins (E-Cadherin)IBA 01/2008 - 01/2002
5	Insulin (Novolin)FDA Link 01/2022 - 12/2008
4	Dopamine Agonists (Dopamine Agonist)IBA 04/2022 - 01/2009
4	Somatostatin Receptors (Somatostatin Receptor)IBA 03/2022 - 06/2007
4	CateninsIBA 06/2021 - 01/2002
4	Follicle Stimulating Hormone (Follitropin)FDA Link 02/2020 - 03/2009
4	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 02/2020 - 01/2009
4	Keratins (Keratin)IBA 01/2013 - 01/2004
4	beta CateninIBA 01/2008 - 01/2002
3	AntibodiesIBA 01/2022 - 07/2013
3	Bromocriptine (Parlodel)FDA LinkGeneric 10/2014 - 01/2012
3	Anterior Pituitary HormonesIBA 03/2013 - 01/2011
3	Protein Isoforms (Isoforms)IBA 03/2012 - 04/2004
3	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 03/2008 - 04/2004
3	gamma Catenin (Plakoglobin)IBA 01/2004 - 01/2002
2	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 06/2022 - 01/2011
2	Capecitabine (Xeloda)FDA Link 04/2022 - 01/2022
2	GlucocorticoidsIBA 06/2021 - 04/2014
2	Ubiquitin-Specific ProteasesIBA 01/2021 - 02/2016
2	MutS ProteinsIBA 04/2020 - 09/2017
2	Estradiol (Delestrogen)FDA LinkGeneric 02/2020 - 07/2019
2	CollagenIBA 09/2017 - 12/2016
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 05/2016 - 12/2008
2	Alkylating AgentsIBA 02/2016 - 03/2013
2	Pharmaceutical PreparationsIBA 02/2016 - 01/2012
2	Corticotropin-Releasing HormoneIBA 01/2015 - 01/2011
2	aryl hydrocarbon receptor-interacting proteinIBA 09/2014 - 04/2007
2	MethyltransferasesIBA 03/2013 - 10/2009
2	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2013 - 03/2012
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 01/2011 - 01/2011
2	Dopamine Receptors (Dopamine Receptor)IBA 01/2011 - 01/2009
2	Luteinizing Hormone (Lutropin)FDA LinkGeneric 03/2010 - 03/2009
2	AntigensIBA 01/2010 - 01/2009
2	Type 4 Fibroblast Growth Factor ReceptorIBA 03/2008 - 09/2007
2	Biological ProductsIBA 01/2008 - 09/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2004 - 01/2003
1	Therapeutic UsesIBA 04/2022
1	amsonic acid (DAS)IBA 04/2022
1	Oral ContraceptivesIBA 03/2022
1	somatostatin receptor 5IBA 03/2022
1	pasireotideIBA 03/2022
1	Testosterone (Sustanon)FDA Link 08/2021
1	Metyrapone FDA Link 06/2021
1	matrigelIBA 06/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 06/2021
1	4-O-carboxymethylascochlorinIBA 01/2021
1	B7-H1 AntigenIBA 04/2020
1	Iodide Peroxidase (Deiodinase)IBA 02/2020
1	anti-thyroglobulinIBA 02/2020
1	thyrotropin-binding inhibitory immunoglobulinIBA 02/2020

Therapy/Procedure

9	Therapeutics 03/2022 - 10/2005
8	Radiotherapy 03/2022 - 01/2002
3	Aftercare (After-Treatment) 10/2014 - 12/2011
2	Adjuvant Radiotherapy 10/2017 - 05/2012
1	Stents 01/2021
1	Chemoradiotherapy 07/2020
1	Drug Therapy (Chemotherapy) 07/2020